The Role Of Botulinum Toxin-A In The Treatment Of Post- Laryngectomy Pharyngocutaneous Fistula

This paper describes our experience in the management of the pharyngocutaneous post-laryngectomy fistula with Botulinum neurotoxin-A injections into both parotid glands. It includes the rationale of the treatment, the physiological and pharmacological basis for this clinical application, the injection technique and the good results achieved. Our findings suggest that Botulinum neurotoxin offers a highly effective, safe and long-lasting conservative treatment in pharyngocutaneous fistula following major oncological pharyngolaryngeal surgery.